:: Volume 6, Issue 2 (Int Biol Biomed J (In press) 2020) ::
IBBJ 2020, 6(2): 0-0 Back to browse issues page
Henoch-Schonlein purpura (HSP) in a rare novel complicated case: A case report
Fariborz Mansour-Ghanaei1 , Iman Soufi Afshar2 , Farahnaz Joukar1 , Afshin Shafaghi * 3, Masoud Baghaei2 , Mahsa Mohtasham2 , Tahereh Zeinali2 , Ali Akbar Samadani2
1- GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran
2- Healthy Ageing Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran
3- Healthy Ageing Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran , drafshinshafaghi@yahoo.com
Abstract:   (2520 Views)
Hcnoch-Schonlein purpura is an IgA mediated small-vessel vasculitis and it is so common in children. The classic term of signs and symbols include polpuble purpura, arthralgia/arthritis, abdominal pain and also renal disease. The incidence of HSP in older age of the entire gastrointestinal tract (gastric, small intestine and large intestine) without arthritis/arthralgia and kidney involvement is rare. In patients with HSP, in older age people, kidney problems are more common than the children, which no kidney problem in this case. A 57-year-old man who was admitted to the Razi Hospital, Rasht, Iran, with Perumblical colicky abdominal pain. During the outpatient surveys, Spiral CT Abdominal-Pelvic with IV oral contrast was determined by abdominal-Pelvic Ultrasonography through small bowel follow, ileum and jejunum involvement. After performing CT, Palpable purpura skin lesions appeared in the upper and lower extremities which was characterized by a low ALB outbreak, S / E (OB +), high fecal calprotectin, high ESR and normal leucocyte. In this way, at Razi Medical Education Center, the endoscopy showed stomach and duodenum involvement and colonoscopy shows the ascending, transverse, and descending colon. Skin sampling shown IgA sediment in Direct Immunofluorescence (DIF). HSP, although it occurs at an early age, has been reported in the patient due to the appearance of skin and abdominal pain and the absence of involvement of other basic organs such as the kidney, lung, and the negative effects of other vasculitis diseases on the basis of skin pathology.
Keywords: Henoch-Schonlein Purpura (HSP), Vasculitis, Abdominal pain
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Type of Study: Case Report | Subject: Other
Received: 2021/01/4 | Accepted: 2021/02/17 | Published: 2021/03/14


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Volume 6, Issue 2 (Int Biol Biomed J (In press) 2020) Back to browse issues page