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Application of Limbal stem cells for regenerative therapy in corneal diseases
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چکیده: (3735 مشاهده) |
Transparency of the cornea as a clear window on the front surface of the eye is an important issue in visual system that a number of ocular surface diseases affect this. The human ocular surface is constructed by two various types of epithelia: the corneal epithelium in center and the conjunctival epithelium that surrounds this. These two epithelia are separated by limbal epithelium which is known as a major source of stem cells. The limbal stem cells (LSCs) provide the source of corneal epithelial renewal and also provide a promising approach to treat chronic epithelial defects on the corneal surface. Therefore, this review summarizes the current knowledge regarding to cornea and ocular surface diseases with special focusses on stem-cell-based therapeutic methods to improve and restore sight in affected patients.
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نوع مطالعه: Review |
موضوع مقاله:
Stem Cell
دریافت: 1401/3/21 | پذیرش: 1401/11/7 | انتشار: 1402/12/8
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