en Pharmacology Pharmacology Short Communication Short Communication <div style="text-align: justify;"><em>Aerva lanata</em> is broadly utilized in urinary issues in Southern part of India as a source of Pashana bheda. A member of <em>Amaranthaceae</em> that is normally known as Gorakha ganja, it is usually located on mountains as weed. Many researches have been carried out to elicit the diuretic and anti-urolithic interest of this plant. It also has been verified for other pharmacological activities like anti-helminthic, anti-hyperglycemic, anti-oxidant, anti-diarrheal, and analgesic. The aim of this study was to evaluate the ethanolic and dichloromethane extracts of leaves of <em>Aerva lanata</em> for their anti-tubercular activity. The anti-tubercular activity of both extracts of <em>Aerva lanata </em>has been evaluated against <em>Mycobacterium tuberculosis </em>H73Rv strain using microplate alamar blue assay (MABA). The activity was documented within MIC range of 0.8 to 100 &mu;g/ml. The results of MABA showed that the dichloromethane extract exhibited remarkable anti-tubercular activity with a MIC comparable to streptomycin<strong>. </strong>It is recommended to isolate the specific phytochemicals responsible for anti-tubercular activity as an alternative source of drug to treat tuberculosis.</div> Aerva lanata leaves, anti-tubercular activity, microplate alamar blue assay 209 212 http://ibbj.org/browse.php?a_code=A-10-201-1&slc_lang=en&sid=1 Harendra Kumar Devarai harendrakumardevarai@gmail.com. 10031947532846002930 10031947532846002930 No Department of Pharmacogonsy, Vignan Pharmacy College, Vadlamudi, Andhra Pradesh, India. Oruganti Sai Koushik kaushikoruganti555@gmail.com. 10031947532846002931 10031947532846002931 No Department of Pharmacogonsy, Vignan Pharmacy College, Vadlamudi, Andhra Pradesh, India. Puttagunta Srinivasa Babu psbabu1@yahoo.co.in. 10031947532846002932 10031947532846002932 No Department of Pharmacogonsy, Vignan Pharmacy College, Vadlamudi, Andhra Pradesh, India. Ramadoss Karthikeyan rkcognosy@gmail.com 10031947532846002933 10031947532846002933 Yes Department of Pharmacogonsy, Vignan Pharmacy College, Vadlamudi, Andhra Pradesh, India.