en Cancer Cancer Case Report Case Report <div style="text-align: justify;">Solitary bone plasmacytoma belongs to a group of lymphoproliferative clinical disorders typified by clonal proliferation of plasma cells. Solitary plasmacytoma typically involves a single bone or extramedullary site. It commonly occurs in the vertebrae or thorax, and rarely involves the mandible. The aim of this report is to present a rare case of solitary plasmacytoma of the jaws mimicking periodontal disease. A solitary plasmacytoma involving the right mandibular ramus/angle was observed in a 60-year-old woman, which was a coincidental finding following persistent excessive post-extraction hemorrhage. The patient was referred for radiotherapy, and subsequent follow up has been uneventful. Although solitary plasmacytoma of the mandible is a rarity, it may occur nonetheless. It may mimic periodontal disease; hence clinicians should have a high index of suspicion when managing patients.</div> Solitary bone plasmacytoma, lymphoproliferative disorders, mandible 67 71 http://ibbj.org/browse.php?a_code=A-10-263-1&slc_lang=en&sid=1 Adebayo Ibikunle adebayoibikunle@gmail.com 10031947532846003054 10031947532846003054 Yes Department of Dental & Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital - - Garba Nadama Road, Sokoto, Nigeria. Abdurrazaq Taiwo droataiwo@yahoo.com 10031947532846003055 10031947532846003055 No Department of Dental & Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital - - Garba Nadama Road, Sokoto, Nigeria. Ramat Braimah robdeji@yahoo.com 10031947532846003056 10031947532846003056 No Department of Dental & Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital Ramat Braimah robdeji@yahoo.com 10031947532846003057 10031947532846003057 No Department of Dental & Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital - - Garba Nadama Road, Sokoto, Nigeria. kabir Abdullahi kabileo08@yahoo.com 10031947532846003058 10031947532846003058 No MBBS; FMCpath Department of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria - - Aliyu Quarters, Sokoto. Michael Adeyemi adebayoibikunle@gmail.com 10031947532846003059 10031947532846003059 No Department of Dental & Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital - - Garba Nadama Road, Sokoto, Nigeria.