en Cancer Cancer Case Report Case Report Acute Lymphoblastic Leukaemia (ALL) a malignant proliferation of immature lymphoid cells is a biologically heterogeneous disorder with variable outcomes in adults. We presents a case of a 52 year old woman who presented with fever, anaemia and peripheral lymphadenopathy of four weeks duration, for which she was managed for disseminated tuberculosis. Complete blood count and a bone marrow aspiration constituted part of her initial investigations. Complete blood count and examination of bone marrow aspiration cytology films were in keeping with acute lymphoblastic leukaemia (ALL-L3). Patient had supportive treatment and managed with Cyclophosphamide, Vincristine (Oncovin), Cytosine Arabinoside and Prednisolone (COAP Regimen), achieved complete clinical and haematologic remission, and has remained disease free after consolidation and maintenance therapy. No evidence of haematologic or clinical relapse at five years and currently in her ninth year post diagnosis and treatment. With high index of suspicion, timely investigation and referral, satisfactory outcomes are achievable in managing some patients with acute lymphoblastic leukaemia. Acute lymphoblastic leukaemia, Cytotoxic chemotherapy, Long term Disease free survival, Jos. 0 0 http://ibbj.org/browse.php?a_code=A-10-358-1&slc_lang=en&sid=1 Ezra Danjuma Jatau ezradjatau@gmail.com 10031947532846003794 10031947532846003794 Yes University of Jos Dele Emmanuel Joseph josephdemmanuel@yahoo.com 10031947532846003795 10031947532846003795 No University of Jos Julie Ochaka Egesie juliegesie@gmail.com 10031947532846003796 10031947532846003796 No University of Jos Obadiah Dapus Damulak ddamulak@yahoo.com 10031947532846003797 10031947532846003797 No University of Jos Tinuade Onyeche Piwuna piwunat@yahoo.com 10031947532846003798 10031947532846003798 No University of Jos Michael Anthony Onoja doctoronoja@yahoo.com 10031947532846003799 10031947532846003799 No Benue State University Ovye Jamus Ewuga ovye_ewuga@yahoo.com 10031947532846003800 10031947532846003800 No Nil Victoria Tapsuk Ma'an mtapsuk@yahoo.com 10031947532846003801 10031947532846003801 No Nil Zakari Ayuba ayubanet@yahoo.com 10031947532846003802 10031947532846003802 No University of Jos