International Biological and Biomedical Journal
IBBJ
Medical Sciences
http://ibbj.org
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admin
2423-4478
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2423
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jalali
1395
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gregorian
2016
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online
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fulltext
en
The Relationship Between Type 2 Diabetes Mellitus and Osteoporosis in Elderly People: a Cross-sectional Study
Clinical Medicine
Clinical Medicine
Original Article
Original Article
<p style="text-align: justify;">Diabetes mellitus (DM) and osteoporosis are common diseases and their prevalence increases with age. Several investigations have indicated that type 1 DM has a significant relationship with bone loss, whereas in type 2 diabetes, this relationship is controversial. Therefore, this study was conducted to determine the relationship between osteoporosis and type 2 DM in elderly people. This population-based study had been carried out on 1151 elderly people in Amirkola, northern Iran. L2-L4 lumbar spine bone mass and the left femoral neck density were measured by dual-energy X-ray absorptiometry (DEXA). In addition, diagnosis of diabetes was done by measuring fasting blood sugar (twice times FBS ≥ 126 mg/dl), according to the WHO criteria or self-reported as well as based on a doctor's prescription. Of total, 362 (31.45%) of patients had DM. The average age of diabetic patients was 68.9± 6.93 years and in non-diabetic group was 68.68± 7.09 years (P= 0.18). The mean L2-L4 lumbar spine bone mass in the diabetic group was 0.90± 0.19 g/cm2 and in the non-diabetic group was 0.85± 0.18 g/cm2 (P= 0.001). The mean lumbar bone mineral density was higher (P= 0.0001) in diabetic men than in non-diabetic men, as well as in women (P= 0.0001). In addition, the mean femoral neck density in diabetic group was 0.85± 0.16 g/cm2 and in the non-diabetic group was 0.84± 0.15 g/cm2 (P= 0.48). Moreover, the femoral neck bone mineral density in diabetic men was higher than in non-diabetics (P= 0.03), whereas in diabetic and non-diabetic women, there was no significant difference (P= 0.52). Our results demonstrated that the mean lumbar and femur bone mineral densities in older people with type 2 DM was higher than people without DM.</p>
Type 2 diabetes mellitus, osteoporosis, bone mineral density
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http://ibbj.org/browse.php?a_code=A-10-117-3&slc_lang=en&sid=1
Mohammad Ali
Bayani
10031947532846001837
10031947532846001837
No
Ahmad
Karkhah
ahmadkarkhah@ymail.com
10031947532846001838
10031947532846001838
No
Seyed Reza
Hoseini
10031947532846001839
10031947532846001839
Yes
Roya
Qarouei
10031947532846001840
10031947532846001840
No
Haji Qorban
Nourodini
10031947532846001841
10031947532846001841
No
Ali
Bijani
10031947532846001842
10031947532846001842
No
Robert G
Cumming
10031947532846001843
10031947532846001843
No