ORIGINAL_ARTICLE Background: Breast cancer is the most common neoplastic cancer of women in the world which accounts for approximately a quarter of all cancers. Methods: In the present review, we aim to evaluate the most common plant and animal products in the food diet recommended for breast cancer treatment in Persian Medicine manuscripts. The findings reveal the retrieved links from the electronic databases between diet, plant and animal products, and cancer through key terms such as plant and animal products; diet, and cancer. Results: The study findings found 17 types of plant and animal products in the food diet. Scientific evidence has investigated that these products can be anticancer agents through several mechanisms including cytotoxicity against MCF cells, being antiproliferative, containing phytosterol, polyphenol, β-sitosterol, flavonoid, antioxidants, as well as having anti-inflammatory and anticancer activities. Conclusion: Nutritional factors play an important factor in the incidence of cancer. In this regard, Persian Medicine mentions nutrition as the first line of therapy. Moreover, pharmacological studies are required to help in the identification of related molecular mechanisms in plant and animal products and their possible side effects. http://ibbj.org/article-1-296-en.pdf 2023-07-01 0 0 Fatemeh Fadaei 1 Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AUTHOR Raefeh Mardi 2 Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AUTHOR Parva Namiranian 3 Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AUTHOR Seyede Nargess Sadati Lamardi n_sadati@sina.tums.ac.ir 4 Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AUTHOR Maliheh Tabarrai dr.mtabarrai@yahoo.com 5 Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AUTHOR

ORIGINAL_ARTICLE Background: Cancer is one of the major causes of mortality in the globe. Several drugs were derived from natural sources such as plants and microorganisms against various types of cancer. Chlorella is a unicellular green alga found in fresh and marine water and is widely used as a food supplement. Chlorella vulgaris protein hydrolysate (CVPH) was tested after being hydrolyzed by pepsin as a gastrointestinal protease.  Methods: The cytotoxic effect on the CT-26 cell line was evaluated using the MTT assay.  Results: The results of toxicity assays showed that the survival rate of the cells was decreased by increasing the concentrations of the peptides (62.5, 125, 250, 500, and 1000 µg/ml). Peptides of <3 kDa molecular weight had a substantial impact on the viability of murine colon cancer cells with an IC50 value of 435 µg/ml. Conclusions: The results of the present study showed that the Chlorella vulgaris hydrolysates protein obtained showed anti-cancer activities against the murine colon cancer (CT-26) cell line. http://ibbj.org/article-1-297-en.pdf 2024-03-05 0 0 Peptides Enzymatic hydrolysate Anticancer activity Colon cancer Chlorella vulgaris Zahra Yghoubzadeh za_yaghoub@yahoo.com 1 Caspian Sea Ecology Research Center (CSERC), Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Sari, Iran AUTHOR Reza Safari 2 Caspian Sea Ecology Research Center (CSERC), Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Sari, Iran AUTHOR

ORIGINAL_ARTICLE An open access scientific journal is a peer-reviewed publication that is available for free online, allowing users to search, read, copy, share the link, download, and print full-text research papers. Urology is a medical practice that focuses on urinary tract problems in both men and women. An urologist is a physician who specializes in the urinary system. Back in the day, doctors would examine a patient's urine for evidence of their illness. Urology, often known as genitourinary surgery, is a surgical and medical specialty that focuses on the male and female urinary tract organs. This paper has analyzed the urology open access journals which are available in DOAJ (Directory of Open Access Journals). The results reveal that DOAJ indexes 12 open access journals published by Elsevier and followed by 8 journals are published by Wolters Kluwer Medknow. The other publishers such as Hindawi Limited 5 journals, Karger Publishers 4 journals. It is found that there are 37 blind peer review journals followed by 32 double blind peer review journals and 11 peer-reviews journals respectively indexed in DOAJ database. It is discovered in the study that maximum journals (74) in Urology are without DOAJ seal and only 8 journals have got the desired DOAJ seal, which represents as a symbol of certification and high publishing standards.   http://ibbj.org/article-1-283-en.pdf 2024-06-11 0 0 Bibliometrics Scientometrics DOAJ OA Urology Open access journals Urologic Symptoms genito-urinary surgery Library Science CHANDRAN VELMURUGAN murugan73@gmail.com 1 Meenakshi Medical College Hospital and Research Institute AUTHOR Munugala Srinivasulu srinu.edu752@gmail.com 2 Sri Krishnadevaraya University AUTHOR

ORIGINAL_ARTICLE Introduction Medication errors occur in all clinical domains, affecting all populations from neonates to elderly. A medication error is any error occurring in the medication-use process. It is a global health concern, since it affect patients and cost the healthcare system billions of dollars annually. Providers should take an active role in maintaining safe medication practices by taking time to instruct patients on when and how to take medications and discuss potential side effects and drug-drug interactions. Modern medicine medical students being the future of health care development should have sufficient knowledge along with a positive attitude and precise practice measures for implementing medication safety. There is paucity of studies regarding this and hence the objective was to describe the knowledge, attitude and practice on medication safety among second year MBBS students of Government Medical College in Kerala. Method  This cross-sectional study was conducted in September 2022 in association with Pharmacovigilance awareness week. All the second MBBS students were requested to participate in the study. A validated questionnaire was prepared by the investigators referring to previous studies and it consisted of 25 questions (9 questions each for knowledge and attitude , 7 questions for practice). The questionnaire was administered as Google Fill Out Form . Results  Among the 167 students of second MBBS ,144 responded giving a response rate of 86.23%. Most of the students were unaware about the precise concept of Pharmacovigilance(83.3%) and root cause analysis in medication safety( 85.4%).The mean total Knowledge score was 3.98±1.736 and the median total Attitude and Practice scores were 6( Interquartile Range-2) and 5( IQR-1) respectively. Conclusion- Majority of the students had positive attitude and satisfactory practice skills even though the knowledge is poor. This necessitates the need of further awareness classes and programme addressing medication safety.   http://ibbj.org/article-1-286-en.pdf 2024-06-11 0 0 Medication safety Medication errors Pharmacovigilance Aravind Vasudevan av6220@gmail.com 1 GMC Kottayam AUTHOR Neethu Mohan neethu.mohan2791@gmail.com 2 GMC Kottayam AUTHOR HariSankar KN harisankar.kn@gmail.com 3 GMC Kottayam AUTHOR Sabeena Kizhedath drsabeenakizhedath@gmail.com 4 GMC Kottayam AUTHOR Dhanya S Palappallil drspdhanya@gmail.com 5 GMC Kottayam AUTHOR

ORIGINAL_ARTICLE ABSTRACT:-   Background:     Injectable Contraceptive is fourth most popular family planning method worldwide after female sterilization, intra uterine contraceptive device & oral contraceptive. Postpartum contraception is crucial for health of women. METHOD:- This was retrospective study from 1st Jan 2020 to 28th Feb 2021 at  tertiary care teaching hospital in pune Aim of study was to know demographic details of DMPA (Depot Metroxy Progesterone Acetate)  users, side effects & compliance of Inj DMPA. Medical record of 117 women  who opted for Inj DMPA after counseling regarding contraceptive options was studied. RESULTS:- Most common side effect observed in Inj DMPA users was menstrual disorder irregular bleeding 62.3% followed by weight gain, amenorrhea & headache in 8.54%,3.41% & 1.7% women respectively. 29% women were para one while majority of DMPA users belonged to 21 to 25 years of age group. CONCLUSION:-        MPA is highly effective, safe, long term reversible contraceptive option. Proper counseling if done before & after administration of Inj DMPA lead to better patient compliance. Key words DMPA, postpartum contraception, family planning,   http://ibbj.org/article-1-288-en.pdf 2024-06-11 0 0 Key words DMPA postpartum contraception family planning Swati Gurav swati.gurav2009@gmail.com 1 Assistant Professor AUTHOR Uma Wankhede drumawankhede@rediffmail.com 2 Professor and head of Department AUTHOR

ORIGINAL_ARTICLE ABSTRACT: Background: One of the important functions of a clinical biochemistry laboratory is clear, accurate, and rapid communication of a critical value to clinicians. Critical values are important and patients require immediate treatment. Patient safety is a cornerstone of healthcare quality, including clinical laboratory services. The present study was aimed to analyse the critical values data in the laboratory settings and compare it with the available data from other studies.  Materials and methods: The present study was conducted at a Subbaiah institute of medical sciences, Shimoga , Karnataka, India over a period of 6 months. The critical values data of several biochemical parameters were obtained from the critical value register. All information accessed was analysed with the main laboratory register of the biochemistry department. The data thus generated was expressed in terms of percentage and presented in tabular form. Results:  A total of 24588 tests were done in our hospital during the study period and 313 critical alerts were generated. Percentage of critical values for each parameters and total tests were recorded.  Our results indicated that the mean percentage of critical values was 1.2% of total tests. This was compared with the other studies which has a value of 2.6% and 6.4% as shown in the table 2. Conclusion: Though our results support the patient safety programregarding regular monitoring and evaluation on the management of laboratory critical values, we still need further studies of critical values in larger scale. Dr Leela P1, Dr ShivarajGowda2, Dr Chandrakant KH3, Dr Shreedhar AM4 1.Associate Professor, Department of Biochemistry, Subbaiah Institute of Medical Sciences, Shivamogga, Karnataka. leelapleela@gmail.com 2.Professor, Department of Biochemistry, Subbaiah Institute of Medical Sciences, Shivamogga, Karnataka. drshivaraj@yahoo.com 3.Prof & Head, Department of Biochemistry, Subbaiah Institute of Medical Sciences, Shivamogga, Karnataka. drckh14@gmail.com 4.Anaesthesiologist, Department of Health and Family Welfare, General Hospital, Channagiri, Karnataka. aanklasam@gmail.com   http://ibbj.org/article-1-289-en.pdf 2024-06-11 0 0 Keywords:Critical value Clinical laboratory Patient safety. Leela P leelapleela@gmail.com 1 Subbaiah Institute of Medical Sciences AUTHOR Chandrakant KH drckh14@gmail.com 2 Subbaiah Institute of Medical Sciences AUTHOR Shreedhar AM aanklasam@gmail.com 3 Subbaiah Institute of Medical Sciences AUTHOR