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Acute Lymphoblastic Leukaemia: A Case Report of Long Term Disease Free Survival in Jos, Nigeria.
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Ezra Danjuma Jatau *1   , Dele Emmanuel Joseph2 , Julie Ochaka Egesie2 , Obadiah Dapus Damulak2 , Tinuade Onyeche Piwuna2 , Michael Anthony Onoja3 , Ovye Jamus Ewuga4 , Victoria Tapsuk Ma'an4 , Zakari Ayuba2 |
1- University of Jos , ezradjatau@gmail.com
2- University of Jos
3- Benue State University
4- Nil |
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Abstract: (4073 Views) |
| Acute Lymphoblastic Leukaemia (ALL) a malignant proliferation of immature lymphoid cells is a biologically heterogeneous disorder with variable outcomes in adults. We presents a case of a 52 year old woman who presented with fever, anaemia and peripheral lymphadenopathy of four weeks duration, for which she was managed for disseminated tuberculosis. Complete blood count and a bone marrow aspiration constituted part of her initial investigations. Complete blood count and examination of bone marrow aspiration cytology films were in keeping with acute lymphoblastic leukaemia (ALL-L3). Patient had supportive treatment and managed with Cyclophosphamide, Vincristine (Oncovin), Cytosine Arabinoside and Prednisolone (COAP Regimen), achieved complete clinical and haematologic remission, and has remained disease free after consolidation and maintenance therapy. No evidence of haematologic or clinical relapse at five years and currently in her ninth year post diagnosis and treatment. With high index of suspicion, timely investigation and referral, satisfactory outcomes are achievable in managing some patients with acute lymphoblastic leukaemia. |
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| Keywords: Acute lymphoblastic leukaemia, Cytotoxic chemotherapy, Long term Disease free survival, Jos. |
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Type of Study: Case Report |
Subject:
Cancer
Received: 2020/02/10 | Accepted: 2021/02/17 | Published: 2021/02/17
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