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:: Volume 1, Issue 2 (Int Biol Biomed J 2015) ::
IBBJ 2015, 1(2): 81-83 Back to browse issues page
The Single Nucleotide Polymorphism rs2305957 is not Associated with Recurrent Pregnancy Loss
Mohammed J Ashour , Fadel A Sharif * 1
1- , fsharif@iugaza.edu.ps
Abstract:   (3330 Views)

This study was conducted in order to investigate the association between the single nucleotide polymorphism (SNP) rs2305957 G/A and recurrent pregnancy loss (RPL) in a group of Palestinian women residing in Gaza strip. A retrospective case-control study was carried out during the period of May to August 2015. A total of 380 females including 190 recurrent pregnancy loss (RPL) patients and 190 control women without previous history of RPL, aged 20–35 years were included in the study. The SNP was analyzed by tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR). No statistically significant difference was found between RPL cases and controls in terms of allelic and genotypic distribution of rs2305957 G/A. SNP rs2305957 G/A does not represent a risk factor for RPL in the investigated population.

Keywords: Recurrent pregnancy loss (RPL), rs2305957, single nucleotide polymorphism (SNP), Gaza Strip, Palestine
Full-Text [PDF 173 kb]   (792 Downloads)    
Type of Study: Original Article | Subject: Genetics & Disease
Received: 2016/01/5 | Accepted: 2016/01/5 | Published: 2016/01/5
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Ashour M J, Sharif F A. The Single Nucleotide Polymorphism rs2305957 is not Associated with Recurrent Pregnancy Loss. IBBJ. 2015; 1 (2) :81-83
URL: http://ibbj.org/article-1-50-en.html


Volume 1, Issue 2 (Int Biol Biomed J 2015) Back to browse issues page
International Biological and Biomedical Journal
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